Publications
Tobin EE, Sharma A, Kros ST, Jima DD, Gray SC and Hall JR. C/EBPβ deficiency enhances keratinocyte apoptosis after UVB-induced DNA damage via regulation of the type I IFN and TNF responses. Front. Cell Death 2025 4:1658598. doi: 10.3389/fceld.2025.1658598
Mills KJ, Doyle M, House JS, Witherspoon JG, Krakko D, Stutts WL, Chappel JR, Hall JR, Baker ES, Smart RC. Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function.PLoS One. 2025 Jun 25;20(6):e0326670. doi: 10.1371/journal.pone.0326670.
Witherspoon JG, Hall JR, Jima D, Atkins HM, Wamsley NT, Major MB, Weissman BE, Smart RC. Mutant Nrf2E79Q enhances the promotion and progression of a subset of oncogenic Ras keratinocytes and skin tumors.Redox Biol. 2024 Sep;75:103261. doi: 10.1016/j.redox.2024.103261. Epub 2024 Jun 28.
House JS, Gray S, Owen JR, Jima DD, Smart RC, Hall JR. C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors. Innate Immun. 2023 Jan;29(1-2):14-24. doi: 10.1177/17534259231162192. Epub 2023 Apr 24.
Tam HW, Hall JR, Messenger ZJ, Jima DD, House JS, Linder K, and Smart RC. C/EBPβ Suppresses Keratinocyte Autonomous Type 1 IFN Response and p53 to Increase Cell Survival and Susceptibility to UVB-induced Skin Cancer. Carcinogenesis. 2019 Jan 29
Messenger ZJ, Hall JR, Jima DD, House JS, Tam, HW and Smart RC. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death and Dis 2018 Oct 15;9(11):1054
Hall, JR, Messenger ZJ, Tam HW, Phillips SL, Recio L and Smart RC. Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. Cell Death and Dis Mar 19:6 e1700 2015
Hall, JR, Bereman MS, Nepomuceno AI, Thompson EA, Muddiman DC and Smart RC. C/EBPα regulates CRL4Cdt2-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint. Cell Cycle 13:3602-3610 2014
Thompson EA, Zhu S, Hall JR, House JS, Ranjan R, Burr JA, He Y-Y, Owens DM and Smart RC. C/EBPα expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPa confers susceptibility to UVB-induced skin squamous cell carcinomas. J. Invest. Dermatol. 131:1339-1346 2011